TOLL-LIKE RECEPTORS IN FAT BODY AND SALIVARY GLAND TISSUES IN THE CATTLE TICK Rhipicephalus microplus
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Keywords

Imunidade inata
corpo gorduroso
glândula salivar
carrapato bovino Innate immune
fat body
salivary gland
cattle tick

How to Cite

Rezende, S. R. da F., Fontenele, M. R., Masuda, C. A., de Oliveira, P. a L., Araujo, H. M. M., Bittencourt, V. R. E. P., & Leite, M. de S. (2016). TOLL-LIKE RECEPTORS IN FAT BODY AND SALIVARY GLAND TISSUES IN THE CATTLE TICK Rhipicephalus microplus. Brazilian Journal of Veterinary Medicine, 38(Supl. 3), 98–102. Retrieved from https://rbmv.org/BJVM/article/view/330

Abstract

ABSTRACT. Rezende S.deF., Fontenele M.R., Masuda C.A., de Oliveira P.L., Araujo H.M.M., Bittencourt V.R.E.P. & Leite M.de S. Toll-like receptors in fat body and salivary gland tissues in the cattle tick Rhipicephalus microplus. [Receptores Toll-like em corpo gorduroso e glândula salivar do carrapato bovino Rhipicephalus microplus]. Revista Brasileira de Medicina Veterinária, 38(supl. 3):47-53, 2016. Programa de Pós-Graduação em Ciências Veterinárias, Anexo 1, Instituto de Veterinária, Universidade Federal Rural do Estado do Rio de Janeiro, BR 465, KM 47, Seropédica, RJ 23890-000, Brasil. E-mail: milaneleite@ufrrj.br Toll-like receptors (TLRs) play an important role in the recognition of pathogen components and subsequent activation of the innate immune response, which then leads to development of immune responses. In arthropods the fat body and salivary glands are important organs in the defense system against invading pathogens. In this study, we identified for the first time the presence of TLRs in fat body and salivary gland tissues of cattle tick Rhipicephalus microplus. Our results show that the expression of TLRs in fat body tissue are not found in all cells, but is specific to some cell types, in salivary glands TLRs protein expression occur in acini structure. We suggest that immune pathways are active in both fat body and salivary glands in the tick. The potential use of TLRs as a target for vaccine formulations against is discussed.

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