Study of the heart rate variability in dogs with brachycephalic syndrome submitted to rhinoplasty surgery
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Keywords

airways diseases
braquicefalic syndrome
autonomic balance
dogs

How to Cite

Filho, M. dos S., Hainfellner, D. C., Lemos, N. M. de O., Macambira, K. D. da S. M. B., Do Carmo, J. S., Alberigi, B. R. S. A. da S., Aben Athar, C. do V., Mendes Junior, A. F., da Veiga, C. C. P., Soares, A. M. B., Botteon, P. de T. L., Fernandes, J. I., & Paiva, J. P. (2021). Study of the heart rate variability in dogs with brachycephalic syndrome submitted to rhinoplasty surgery. Brazilian Journal of Veterinary Medicine, 42(1), e104920. https://doi.org/10.29374/2527-2179.bjvm104920

Abstract

The aim of the present study was to evaluate the HRV in the brachycephalic races, before and after surgical correction of the stenosis of the nostrils, by means of prolonged electrocardiography, observing the excess of the parasympathetic stimulation regarding the occurrence of bradyarrhythmias and their clinical consequences, and possibility of improvement of the autonomic balancing after the treatment, increasing the quality and life expectancy of these patients. Sixteen dogs with nostril stenosis were included, where the analysis and progression of the HRC findings at different moments before the surgical procedure (day 0) and after the procedure were performed in two moments, 30 and 60 days. The technique of alavestibulplasty was performed and HRV analysis was recorded by means of prolonged electrocardiography. For this examination, the indexes were analyzed in the time domain. Regarding the clinical findings, there was an improvement in the evaluation of the heart and respiratory rate, as well as a reduction in parasympathetic activity, as shown in the bradyarrhythmias. Regarding the HRV indexes in the time domain, rMSSD and SDNN associated with mean heart rate findings, have brought strong indications that the reduction of parasympathetic stimulation is related to the reduction of HRV in these animals. The rMSSD is the HRV index in the domain of the time that early changed can be used as indicator of the increase of the parasympathetic activity caused by the Brachycephalic Syndrome

https://doi.org/10.29374/2527-2179.bjvm104920
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References

Acierno, M. J., Brown, S., Coleman, A. E., Jepson, R. E., Papich, M., Stepien, R. L., & Syme, H. M. (2018). ACVIM consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. Journal of Veterinary Internal Medicine, 32(6), 1803-1822. http://dx.doi.org/10.1111/jvim.15331. PMid:30353952.

Aubert, A. E., Seps, B., & Beckers, F. (2003). Heart rate variability in athletes. Sports Medicine, 33(12), 889-919. http://dx.doi.org/10.2165/00007256-200333120-00003. PMid:12974657.

Bofan, A. B., Ionascu, I., & Șonea, A. (2015). Brachycephalic airway syndrome in dogs. Scientific Works. Series C, Veterinary Medicine, 61(1), 103-112.

Boon, J. A. (2005). Ecocardiografia em Modo-M: uma avaliação quantitativa. In J. A. Boon (Ed.), Ecocardiografia Bidimensional e em Modo-M para o clínico de pequenos animais. (1st ed., pp. 39-52). Wyoming: Roca.

Bosquet, L., Gamelin, F. X ., & Berthoin, S. (2007). Is aerobic endurance a determinant of cardiac autonomic regulation? European Journal of Applied Physiology, 100(3), 363-369. http://dx.doi.org/10.1007/s00421-007-0438-3. PMid:17440748.

Chua, K. C., Chandran, V., Acharya, U. R., & Lim, C. M. (2008). Cardiac state diagnosis using higher order spectra of heart rate variability. Journal of Medical Engineering & Technology, 32(2), 145-155. http://dx.doi.org/10.1080/03091900601050862. PMid:18297505.

De Giorgio, C. M., Miller, P., Meymandi, S., Chin, A., Epps, J., Gordon, S., Gornbein, J., & Harper, R. M. (2010). RMSSD, a measure of vagus-mediated heart rate variability, is associated with risk factors for SUDEP: the SUDEP-7 Inventory. Epilepsy & Behavior, 19(1), 78-81. http://dx.doi.org/10.1016/j.yebeh.2010.06.011. PMid:20667792.

Doxey, S., & Boswood, A. (2004). Differences between breeds of dog in a measure of heart rate variability. The Veterinary Record: Oxford, 154(1), 713-717. http://dx.doi.org/10.1136/vr.154.23.713. PMid:15214514.

Fossum, T. W., & Duprey, L . P. (2005). Cirurgias do trato respiratório superior. In T. W. Fossum (Ed.), Cirurgia de pequenos animais (3th ed., p. 923-929). São Paulo: Rocca.Goldberger, J. J. (1999). Sympathovagal balance: How should we measure it? American Journal of Physiology. Heart and Circulatory Physiology, 276(1), 1273-1280. http://dx.doi.org/10.1152/ajpheart.1999.276.4.H1273. PMid:10199852.

Kleiger, R. E., Stein, P. K ., & Bigger Junior, J. T. (2005). Heart rate variability: Measurement and clinical utility. Annals of Noninvasive Electrocardiology: Armonk, 10(1), 88-101. http://dx.doi.org/10.1111/j.1542-474X.2005.10101.x. PMid:15649244.

Logier, R., De Jonckheere, J., & Dassonneville, A. (2004). An efficient algorithm for R-R intervals series filtering. Conference Proceedings:... Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 6(1), 3937-3940. http://dx.doi.org/10.1109/IEMBS.2004.1404100. PMid:17271158.

Malik, M., Bigger, J. T., Camm, A. J., Kleiger, R. E., Malliani, A., Moss, A. J., & Schwartz, P. J. (1996). Heart rate variability: standards of measurement, physiological interpretation, and clinical use. European Heart Journal, London, 17(3), 354-381. http://dx.doi.org/10.1093/oxfordjournals.eurheartj.a014868. PMid:8737210.

Moraes, P. (2012). Síndrome Aérea dos Braquicefálicos – Estenose de Narina em Cão: Relato de Caso. Revista Científica Eletrônica de Medicina Veterinária, 18(1), 1-8.Paiva, J. P. (2005). Paralisis de Laringe. In: C. J. Mucha, C. Sorribas, & F. C. Pellegrino (Eds.), Consulta Rapida em La Clinica Diaria (1st ed., pp. 17-20). Buenos Aires: Inter-Médica.

Park, D. H., Shin, C. J., Hong, S. C., Yu, J., Ryu, S. H., Kim, E. J., Shin, H. B., & Shin, B. H. (2008). Correlation between the severity of obstructive sleep apnea and heart rate variability indices. Journal of Korean Medical Science, 23(2), 226-231. http://dx.doi.org/10.3346/jkms.2008.23.2.226. PMid:18437004.

Paschoal, A., Petreluzzi, S., & Gonçalves, O. (2002). Estudo da variabilidade da frequência cardíaca em pacientes com doenças pulmonar obstrutiva crónica. Revista Ciencia Médica, 11(1), 27-37.

Penttilä, J., Helminen, A., Jartti, T., Kuusela, T., Huikuri, H . V., Tulppo, M . P., Coffeng, R., & Scheinin, H. (2001). Time domain, geometrical and frequency domain analysis of cardiac vagal outfow: effects of various respiratory patterns. ClinicalPhysiology, 21(3), 365-376. PMid:11380537.

Pumprla, J., Howorka, K., Groves, D., Chester, M., & Nolan, J. (2002). Functional assessment of heart rate variability: physiological basis and practical applications. International Journal of Cardiology, 84(1), 1-14. http://dx.doi.org/10.1016/S0167-5273(02)00057-8. PMid:12104056.

Radespiel-Tröger M., Rauh R., Mahlke C., Gottschalk T. & Muck-Weymann, M. Agreement of two different methods for measurement of heart rate variability. ClinicalAutonomicResearch,13(2):99-102, 2003.

Rajendra Acharya, U., Paul Joseph, K., Kannathal, N., Lim, C. M., & Suri, J. S. (2006). Heart rate variability: A review. Medical & Biological Engineering & Computing, 44(12), 1031-1051. http://dx.doi.org/10.1007/s11517-006-0119-0. PMid:17111118.

Rasmussen, C. E., Falk, T., Zois, N. E., Moesgaard, S. G., Häggström, J., Pedersen, H. D., Ablad, B., Nilsen, H . Y., & Olsen, L. H. (2012). Heart rate, heart rate variability, and arrhythmias in dogs with myxomatous mitral valve disease. Journal of Veterinary Internal Medicine, 26(1), 76-84. http://dx.doi.org/10.1111/j.1939-1676.2011.00842.x. PMid:22151356.

Rozanski, E. A. (2015). Oxygenation and ventilation. Veterinary Clinical Small Animals, 46(1), 1-10. PMid:26051823.Sampaio, I. (2002). Estatística aplicada a experimentação animal (2nd ed., 265 p.). Belo Horizonte: Fundação de Estudo e Pesquisa em Medicina Veterinária e Zootecnia.

Santos, M. D. B., Moraes, F. R ., Marães, V. R. F. S., Sakabe, D. I., Takahashi, A. C. M., Oliveira, L., Gallo Junior, L., Silva, E., & Catai, A. M. (2013). Estudo da arritmia sinusal respiratória e da variabilidade da frequência cardíaca de homens jovens e de meia-idade. Revista da Sociedade de Cardiologia do Estado de São Paulo, 13(3 Supl A), 15-24.

Shields Junior, R . W. (2009). Heart rate variability with deep breathing as a clinical test of cardiovagal function. Cleveland Clinic Journal of Medicine, 76(Suppl 2), S37-S40. http://dx.doi.org/10.3949/ccjm.76.s2.08. PMid:19376980.

Song, J., Ogawa, M., Tan, A . Y., Chen, P., & Lin, S. (2006, August 30 - September 3). Heart rate variability and autonomic nerve activities in ambulatory dogs. In IEEE Engineering in Medicine and Biology Society, EMBS Annual International Conference (pp. 1780-1783). New York, NY: EMB Executive Office.

Thuraisingham, R. A. (2006). Preprocessing RR interval time series for heart rate variability analysis and estimates of standard deviation of RR intervals. Computer MethodsandProgramsBiomedicine, 83(1), 78-82. http://dx.doi.org/10.1016/j.cmpb.2006.05.002. PMid:16806571.

Tilley, L . P. (1992). Essential of canine and feline electrocardiography (3rd ed., 470 p.). Philadelphia: Lea & Febiger.

Tilley, L . P., & Smith Junior, F. W. (2008). Eletrocardiography. In L. P. Tilley, F. W. Smith Junior, M. A. Oyama & M. M. Sleeper (4th ed., 49 p). Manual of canine and feline cardiology. Missouri: Saunders Elsevier.

Vanderlei, L. C. M., Pastre, C. M., Hoshi, R. A., Carvalho, T. D., & Godoy, M . F. (2009). Noções básicas de variabilidade da frequência cardíaca e sua aplicabilidade clínica. Revista Brasileira de Cirurgia Cardiovascular, 24(2), 205-217. http://dx.doi.org/10.1590/S0102-76382009000200018. PMid:19768301.

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Copyright (c) 2019 Mário dos Santos Filho, Daniel Carvalho Hainfellner, Karen Denise da Silva Macambira Barbosa Macambira, Juliana Silva Do Carmo, Nathália Marques de Oliveira Lemos, Bruno Ricardo Soares Alberigi da Silva Alberigi, Cristiano Chaves Pessoa da Veiga, Ana Maria Barros Soares, Paulo de Tarso Landgraf Botteon, Jonimar Pereira Paiva, Julio Israel Fernandes