http://rbmv.org/index.php/BJVM/issue/feed Brazilian Journal of Veterinary Medicine 2020-07-07T23:57:23-03:00 Carlos Wilson Gomes Lopes contato.rbmv@gmail.com Open Journal Systems <pre id="tw-target-text" class="tw-data-text tw-ta tw-text-small" dir="ltr" data-placeholder="Tradução" data-fulltext=""><span lang="en"><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">O Jornal Brasileiro de Medicina Veterinária (BJVM) é o jornal oficial da Sociedade de Medicina Veterinária do Rio de Janeiro (Somverj). <br></span><span style="vertical-align: inherit;">Como uma política editorial, publica artigos científicos originais, revisões (no convite do Editor) e relatos de casos. <br></span><span style="vertical-align: inherit;">Em todos os campos da Medicina Veterinária. </span></span><br></span></pre> http://rbmv.org/index.php/BJVM/article/view/1008 Detomidine and xylazine, at different doses, in donkeys (Equus asinus) 2020-05-27T10:49:31-03:00 Roberta Nunes Parentoni roberta.parentoni@gmail.com Fernanda Vieira Henrique nandinhavh@gmail.com Arthur Willian de Lima Brasil arthurbrasil@unir.com.br Rafaela Alves Dias rafa.ad@hotmail.com Ana Lucélia de Araújo Araújo araujonascal@gmail.com Rodrigo de Souza Mendes rodrigo.souza.mendes@gmail.com Emanuel Ferreira Martins Filho gugaossa@gmail.com João Moreira da Costa Neto jmcn@ufba.br Almir Pereira de Souza almirpsouza@ibest.com.br Pedro Isidro da Nóbrega Neto pedroisidro@ymail.com <p>The effects of detomidine and xylazine in northeasters donkeys were compared. Six animals participated, randomly, of all experimental groups: xylazine 10%, 0.8 mg/kg (xylazine group 0.8 - GX0.8), 1.0 mg/kg (GX1.0) and 1, 2 mg/kg (GX1.2); and detomidine 1%, 0.02 mg/kg (Detomidine group 0.02 - GD0.02), 0.04 mg/kg (GD0.04) and 0.06 mg/kg (GD0.06) intravenous. Heart rate (HR) and respiratory rate (RR), rectal temperature (RT), mean arterial pressure (MAP), blood glucose, sedation, analgesia, ataxia, arrhythmias and urination were monitored. Duration of sedation was greater in the groups in which detomidine was administered. The muzzle-soil distance significantly reduced in all groups five minutes after the sedative administration, remaining smaller for a longer time in the GD0.06. Ataxia in GX1.0 was greater than in GX0.08 and GX1,2, being equivalent to GD0,04 and GD0,06. Analgesia lasted 30 minutes in GD0.06 and 10 minutes in the others. There was reduction of HR in GD0.02 and GD0.04 and atrioventricular block. There was a reduction in TR in GX1,2, GD0.02, GD0,04 and GD0,06. RR decreased in all groups. MAP increased in GD0.02, GD0.04 and GD0.06 five, 20, 30 and 10 minutes after administration of detomidine, respectively. Hyperglycaemia occurred for 120 minutes in all animals receiving detomidine. The frequency of micturition was higher in GD0.06 (2.2 ± 0.8) than in GX0.8 (0.8 ± 0.4). In northern Brazil, detomidine and xylazine promote short duration analgesia and cardiorespiratory alterations, but detomidine causes a greater sedative, hypertensive and hypothermic effect.</p> 2020-01-23T00:00:00-02:00 Copyright (c) 2020 Fernanda Vieira Henrique, Roberta Nunes Parentoni, Arthur Willian de Lima Brasil, Rafaela Alves Dias, Ana Lucélia de Araújo Araújo, Rodrigo de Souza Mendes, Emanuel Ferreira Martins Filho, João Moreira da Costa Neto, Almir Pereira de Souza, Pedro Isidro da Nóbrega Neto http://rbmv.org/index.php/BJVM/article/view/1012 Intestinal and immunological histological parameters of broilers supplemented with commercial probiotic or fungi of the autochthonous microbiota 2020-03-01T21:56:00-03:00 Flávia Oliveira Abrão flavia.abrao@ifgoiano.edu.br Danne Kelle Siqueira Lima danny-lima2012@hotmail.com Moisés Sena Pessoa moisessena@yahoo.com.br <p>Objetivou-se avaliar a histomorfometria das porções intestinais de frangos de corte suplementados com probiótico, bem como parâmetros histológicos de órgãos vinculados ao sistema imune. O fungo avaliado <em>Rhizomucor</em> spp. é proveniente de amostras do conteúdo intestinal de frangos Cobb 500. Este foi selecionado <em>in vitro</em> quanto características probióticas e encaminhado para ensaio de desempenho. Foi utilizado um delineamento inteiramente ao acaso com 3 tratamentos e 7 repetições. Uma ave por unidade experimental aos 21 e 42 dias de idade foi sacrificada e, os órgãos foram amostrados, após fixação foram submetidos à desidratação e diafanização e, em seguida, analisados por microscopia óptica e submetidos à análise de histomorfometria e pesquisados pontos que indicavam lesão. Observou-se aos 21 dias que as aves pertencentes ao grupo probiótico formulado a base de <em>Rhizomucor </em>spp. apresentaram maior altura de vilo no duodeno. Também constatou-se um aumento significativo na altura de vilo do jejuno para o grupo controle e probiótico formulado a base de <em>Rhizomucor</em> spp.. Aos 42 dias observou-se, apenas diferença para profundidade de cripta com uso do probiótico comercial para duodeno. Referente as análises das alterações teciduais dos intestinos, baço e bursa aos 21 dias, cem por cento das aves recebendo o fungo <em>Rhizomucor</em> spp. não apresentaram alterações histológicas e aos 42 dias foram observadas alterações na bursa em dois animais. A inclusão do potencial probiótico fúngico <em>Rhizomucor</em> spp. na dieta de frangos de corte aos 21 dias de idade promove maior altura de vilo e aos 42 dias de idade não houve influência.</p> 2020-01-23T00:00:00-02:00 Copyright (c) 2020 Flávia Oliveira Abrão, Danne Kelle Siqueira Lima, Moisés Sena Pessoa http://rbmv.org/index.php/BJVM/article/view/1042 Ultrasonographic evaluation of the reproductive tract as predictor of pregnancy in Girolando heifers submitted to Timed Artificial Insemination 2020-03-22T23:27:48-03:00 Lara Nogueira Silenciato larasilenciato@hotmail.com Joaquim Esquerdo Ferreira esquerdovet@gmail.com Samuel Rodrigues Bonamichi do Couto samuel_piquete@yahoo.com.br Otávia Reis e Silva otaviareis@hotmail.com Osvaldo Almeida Resende oaresende@uol.com.br Andressa Ferreira da Silva andressaspyrides@gmail.com Helcimar Barbosa Palhano helcimarpalhano@gmail.com Marco Roberto Bourg de Mello mmello@ufrrj.br <p>The objective of this study was to evaluate the influence of the degree of uterine and ovarian development on the pregnancy rate of Girolando heifers submitted to Timed Artificial Insemination (TAI). Fifty-six heifers, representing 100% of the category in the herd studied, were evaluated. The heifers were submitted to a gynecological evaluation, prior to hormonal treatment, with ultrasonography, in order to measure the diameter of the uterine horns and ovaries, as well as evaluate the presence of corpus luteum (CL) and antral follicles. According to the values found for the uterine and ovarian diameters, the animals were classified into scores from one to three. After the gynecological evaluation, all animals were submitted to TAI. There was no statistical difference (P&gt;0.05) in pregnancy rates between the different uterine and ovarian scores, as well as in relation to ovarian structures. However, a statistical difference (P&lt;0.05) was observed in the percentage of animals in anestrous within ovarian scores one, two and three (83.3%, 37.5% and 42.8%, respectively). The conclusion was that uterine and ovarian development did not interfere in the pregnancy rate of Girolando heifers in the herd studied.</p> 2020-01-23T00:00:00-02:00 Copyright (c) 2020 Lara Nogueira Silenciato, Joaquim Esquerdo Ferreira, Samuel Rodrigues Bonamichi do Couto, Otávia Reis e Silva, Osvaldo Almeida Resende, Andressa Ferreira da Silva, Helcimar Barbosa Palhano, Marco Roberto Bourg de Mello http://rbmv.org/index.php/BJVM/article/view/1049 Study of the heart rate variability in dogs with brachycephalic syndrome submitted to rhinoplasty surgery 2020-03-30T12:24:42-03:00 Mário dos Santos Filho mariosantoscg@gmail.com Daniel Carvalho Hainfellner dhainfellner@gmail.com Nathália Marques de Oliveira Lemos nathycardiovet@gmail.com Karen Denise da Silva Macambira Barbosa Macambira karendenisemacambira@gmail.com Juliana Silva Do Carmo docarmo.julianas@gmail.com Bruno Ricardo Soares Alberigi da Silva Alberigi bruno.alberigi@gmail.com Carolina do Valle Aben Athar carolathar@msn.com Aguinaldo Francisco Mendes Junior aguinaldo_zootec@hotmail.com Cristiano Chaves Pessoa da Veiga radiovet@ufrrj.br Ana Maria Barros Soares anasoaresvet@gmail.com Paulo de Tarso Landgraf Botteon paulobotteon@gmail.com Julio Israel Fernandes vetjulio@yahoo.com.br Jonimar Pereira Paiva jonimarpaiva@uol.com.br <p>The aim of the present study was to evaluate the HRV in the brachycephalic races, before and after surgical correction of the stenosis of the nostrils, by means of prolonged electrocardiography, observing the excess of the parasympathetic stimulation regarding the occurrence of bradyarrhythmias and their clinical consequences, and possibility of improvement of the autonomic balancing after the treatment, increasing the quality and life expectancy of these patients. Sixteen dogs with nostril stenosis were included, where the analysis and progression of the HRC findings at different moments before the surgical procedure (day 0) and after the procedure were performed in two moments, 30 and 60 days. The technique of alavestibulplasty was performed and HRV analysis was recorded by means of prolonged electrocardiography. For this examination, the indexes were analyzed in the time domain. Regarding the clinical findings, there was an improvement in the evaluation of the heart and respiratory rate, as well as a reduction in parasympathetic activity, as shown in the bradyarrhythmias. Regarding the HRV indexes in the time domain, rMSSD and SDNN associated with mean heart rate findings, have brought strong indications that the reduction of parasympathetic stimulation is related to the reduction of HRV in these animals. The rMSSD is the HRV index in the domain of the time that early changed can be used as indicator of the increase of the parasympathetic activity caused by the Brachycephalic Syndrome</p> 2020-01-23T00:00:00-02:00 Copyright (c) 2019 Mário dos Santos Filho, Daniel Carvalho Hainfellner, Karen Denise da Silva Macambira Barbosa Macambira, Juliana Silva Do Carmo, Nathália Marques de Oliveira Lemos, Bruno Ricardo Soares Alberigi da Silva Alberigi, Cristiano Chaves Pessoa da Veiga, Ana Maria Barros Soares, Paulo de Tarso Landgraf Botteon, Jonimar Pereira Paiva, Julio Israel Fernandes http://rbmv.org/index.php/BJVM/article/view/1072 Chemical immobilization of free-living capybaras (Hydrochoerus hydrochaeris) using ketamine-dexmedetomidine combination and a remote drug delivery system 2020-06-16T10:29:45-03:00 DEREK ROSENFIELD dro@usp.br Mario Ferraro maferraro@usp.br Claudia Igayara claudiaigayara@uol.com.br Silvia Renata Gaigo Cortopassi silcorto@usp.br Cristiane Schilbach Pizzutto crissp@usp.br <p>Capturing wild capybaras for scientific projects, population control or medical interventions is a growing necessity. With this study, we intended to evaluate a Ketamine/Dexmedetomidine as a reversible chemical restraint in free-ranging synanthropic capybaras, seeking enhanced anesthetic and recovery characteristics while testing a specialized remote drug delivery system (RDDS). For this purpose, 18 adult capybaras (male n = 8; females n = 10) (67.3 ± 9.45 kg), prior to chemical restraint, were physically confined, subsequently darted intramuscularly with 9 mg kg<sup>-1</sup> ketamine and 0,005 mg kg<sup>-1</sup> dexmedetomidine. Post-intervention, 0,005 mg kg<sup>-1</sup> atipamezole, administered IM, was used as a reversal agent (RA), (n = 5). Anesthetic effects were recorded as latency period (LP I/first observed effects) (LP II /lateral recumbency plus time to handle the animal). Recovery time was divided into (R1/no RA, fully recovered/ready for release), (R2a/R2b, with RA, time to ambulant position plus time to full recovery/release, respectively). Vital signs were recorded at a 15-minute interval. GraphPad Prism 8.1.1 was used to perform unpaired t-test, with a p-value ˂ 0,05 considered significant. Results: Mean LP I: 3 ± 1 min.; LP II: 10 ± 2 min. Procedure duration: 49 ± 5 min. Recovery time without RA, (R1): 55 ± 15 min., compared to 18 min., with RA (R2a) to ambulant position (with severe discoordination), requiring additional time until full recovery (ready for release): ± 45 min (R2b). Total time, to release (R2a/b): mean ± SD = 67 ± 13.85 min. Concluding for clinical relevance that the association of Ketamine and Dexmedetomidine performed satisfactorily, providing effective sedation and analgesia, and relative short latency periods. Used RA did not shorten total recovery time significantly (P-value = 0,7328). Adverse effects such as the risk of acute cecal tympany, due to the lack of pre-anesthetic fasting, concurrent to collateral effects of injectable and volatile anesthetics on the motility of the digestive tract, and induced bradycardia/hyperthermia warrant extra caution. The employed RDDS provided reliable drug delivery under field conditions.</p> 2020-04-17T00:00:00-03:00 Copyright (c) 2020 DEREK ROSENFIELD, Mario Ferraro, Claudia Igayara, Silvia Renata Gaigo Cortopassi, Cristiane Schilbach Pizzutto http://rbmv.org/index.php/BJVM/article/view/1074 Methicillin-resistant Staphylococcus pseudintermedius: an underestimated risk at pet clinic 2020-07-07T23:57:23-03:00 Theresse Holmstrom theresseholmstrom@yahoo.com.br Luria Adib David luria.adib@hotmail.com Cássia Couto da Motta ca.damotta@hotmail.com Thomas Hebert dos Santos santosthomas149@gmail.com Irene da Silva Coelho irenecs@yahoo.com Shana de Mattos de Oliveira Coelho shana_mattos@hotmail.com Dayanne Araújo de Melo daymelo.com@gmail.com Miliane Moreira Soares de Souza milianemss@gmail.com <p>The prevalence of methicillin-resistant <em>Staphylococcus pseudintermedius</em> (MRSP) as a cause of infectious disease in companion animals remains unknown. The emergence of MRSP is a challenge in veterinary medicine as multidrug-resistant strains began to emerge, resulting in treatment failures. This study provides an overview of the characterization of <em>S. pseudintermedius</em> strains from clinical pet samples and the prevalence of MRSP strains. A total of 123 <em>S. pseudintermedius</em> strains were characterized by phenotypic testing and the MALDI-TOF technique and evaluated for susceptibility to methicillin and the presence of the <em>mec</em>A gene. Of these, 49 (39.8%) were identified as MRSP. The results confirm the importance of monitoring resistant pathogens and the need for further studies to determine the prevalence of MRSP in companion animals. The prevalence of methicillin-resistant <em>Staphylococcus pseudintermedius</em> (MRSP) as a cause of infectious disease in companion animals remains unknown. The emergence of MRSP is a challenge in veterinary medicine as multidrug-resistant strains began to emerge, resulting in treatment failures. This study provides an overview of the characterization of <em>S. pseudintermedius</em> strains from clinical pet samples and the prevalence of MRSP strains. A total of 123 <em>S. pseudintermedius</em> strains were characterized by phenotypic testing and the MALDI-TOF technique and evaluated for susceptibility to methicillin and the presence of the <em>mec</em>A gene. Of these, 49 (39.8%) were identified as MRSP. The results confirm the importance of monitoring resistant pathogens and the need for further studies to determine the prevalence of MRSP in companion animals.</p> 2020-07-01T00:00:00-03:00 Copyright (c) 2020 Theresse Holmstrom, Luria Adib David , Cássia Couto da Motta, Thomas Hebert dos Santos, Irene da Silva Coelho, Shana de Mattos de Oliveira Coelho, Dayanne Araújo de Melo, Miliane Moreira Soares de Souza http://rbmv.org/index.php/BJVM/article/view/1080 ANIMAL HEALTH SURVEILLANCE BY QUADRANT - A NEW "INTELLIGENT" AGRICULTURAL SURVEILLANCE SYSTEM 2020-07-01T11:06:38-03:00 Francisco Bezerra de Carvalho Neto cabrabom.bomcabra@yahoo.com.br Franco Zanandreis fzanandreis@iagro.ms.gov.br Clayton Bernardinelli Gitti cbgitti@yahoo.com.br <p>Brazil is the world's greatest beef exporter and Mato Grosso do Sul state is one of the most relevant states of Brazil with utmost importance for animal production. To ensure the health of the animal herd, the Livestock Defense services of all federative units perform securities activities, although not as effective as they should be, following the procedures of the Ministry of Agriculture, Livestock and Supply (MAPA). This study aims to present a brand new health surveillance system established in Mato Grosso do Sul state where each city was mapped in blocks and ranked by hazard levels. An activity planning is carried out in which all city blocks receive livestock defense surveillance. The actions are tracked and registered through GPS devices and the data are assessed by satellites images analyzer software. Therefore, the actions are auditable and the results monthly analyzed for future actions planning. As a result, the surveillance actions ceased to be performed on demand and started to cover not only the areas next to the local office but the entire city areas as well; the registration's and sanitary program's data were updated and activities had become clear and auditable, allowing all actions of the Health Defense services to be controlled and monitored. It is known that, once these actions are implemented in other federative units it may lead to a differential advantage to Brazilian Health Defense Services.</p> 2020-05-19T00:00:00-03:00 Copyright (c) 2020 Francisco Bezerra de Carvalho Neto, Franco Zanandreis, Clayton Bernardinelli Gitti http://rbmv.org/index.php/BJVM/article/view/1062 Complex Leopard non-associated congenital night blindness in Mangalarga Marchador foals 2020-05-04T23:38:39-03:00 Daniele Mancilha Carneiro leoveterinariojf@gmail.com Camilla Espíndula Mendonça leoveterinariojf@gmail.com Maurílio Rosa leoveterinariojf@gmail.com Denise Monnerat Nogueira leoveterinariojf@gmail.com Leonardo Rodrigues de Lima leoveterinariojf@gmail.com <p>The report describes two cases of four- and five-month-old Mangalarga Marchador fillies showing signs of night blindness. The animals appeared to have disorientation at night. Ophthalmic examination revealed all parameters as normal except for the absence of menace response in the penumbra. Fundoscopy examination did not demonstrate any morphological abnormalities in the retina. Electroretinography examination confirmed a failure in the electrical activity of rods, which are retinal photoreceptors responsible for night vision. However, we noted a small reduction in the electrical activity of the cones, suggesting that the animals may have visual difficulties in clear environments. Genomic analysis of the hair follicles from their mane (Veterinary Genetics Laboratory/UC – Davis, USA) did not reveal the presence of homozygosity for the Leopard Complex, a gene pool associated with congenital stationary nocturnal blindness (CSNB) in horses with depigmented hair. Outcomes of the studbook analysis suggested the presence of kinship among the described animals. Additional research is required for the genomic determination of nocturnal blindness in Mangalarga Marchador horses.&nbsp;</p> 2020-04-18T00:00:00-03:00 Copyright (c) 2020 Daniele Mancilha Carneiro, Camilla Espíndula Mendonça, Maurílio Rosa, Denise Monnerat Nogueira, Leonardo Rodrigues de Lima http://rbmv.org/index.php/BJVM/article/view/1063 ACQUIRED MYASTHENIA GRAVIS IN DOG – CASE REPORT 2020-06-10T23:48:02-03:00 Maria Eduarda dos Santos Lopes Fernandes dudalopesfer@hotmail.com Gabriela Wacheleski Brock gwacheleski@gmail.com Anna Julia Rodrigues Peixoto anjuroi.ajp@gmail.com Clarice Gonring Corrêa claricegonring@gmail.com Patricia de Oliveira patricia.rjvet@yahoo.com.br Alex Gradowski Adeodato alexadeodato@crvimagem.com.br Marta Fernanda Albuquerque da Silva martafasilva@gmail.com Cássia Maria Molinaro Coelho cassiamaria.coelho@gmail.com <p>Neuromuscular diseases are uncommon in the clinical routine of dogs and cats and their diagnosis is a challenge for the veterinarian. Thus, this paper reports the clinical diagnosis and established therapy in a four-year-old female without a defined breed with a history of ataxia and tetraparesis, especially after exercise. Due to the history and clinical signs presented, acquired myasthenia gravis was suspected and the therapeutic diagnosis was chosen using anticholinesterase neostigmine, for being simpler, faster and more accessible. The patient presented a significant improvement in clinical status after administration of neostigmine intramuscularly, returning to normal ambulatory activity after administration of the drug intravenously, thus making possible the diagnosis of the disease. Treatment was instituted using pyridostigmine bromide associated with corticosteroid in a immunosuppressive dose for a period of six months, observing complete remission of the clinical signs without recurrences until the present moment.</p> 2020-05-05T00:00:00-03:00 Copyright (c) 2020 Maria Eduarda dos Santos Lopes Fernandes, Gabriela Wacheleski Brock, Anna Julia Rodrigues Peixoto, Clarice Gonring Corrêa, Patricia de Oliveira, Alex Gradowski Adeodato, Marta Fernanda Albuquerque da Silva, Cássia Maria Molinaro Coelho http://rbmv.org/index.php/BJVM/article/view/1078 Renal nephroblastoma in adult dog 2020-07-01T11:57:16-03:00 Dayane Caicó Collares Araujo dayanecaico@hotmail.com Michel Alves da Silva michel@ufsj.edu.br Cristiano Chaves Pessoa da Veiga veiga@imagemveterinaria.com.br Julio israel Fernandes vetjulio@yahoo.com.br <p>Nephroblastoma is a neoplasia originating from the poor differentiation of the metanephrogenic blastema, therefore neoplasia of embryonic origin. It is commonly reported in dogs less than two years old and is rare in adults. Clinical signs include hematuria, polyuria and palpable abdominal mass. Surgery is elective therapy. Chemotherapy depend on the stage of the disease. The purpose of this paper is to report a case of nephroblastoma in a mixed-breed, six-year-old male canine with a stage I nephroblastoma (according to human staging for Wilm's tumor). The patient performed clinically well and without changes in the staging exams (thorax radiographs). The initial complete blood count indicated only lymphopenia and biochemical profile without alterations. Abdominal ultrasound showed vascularized formation with no defined limits, cystic, with probable origin in left kidney, dislocating liver and spleen. The recommended treatment was total nephrectomy. Kidney size was about 25.0 cm in diameter, with irregular surface. Numerous cysts were present and were covered by a capsule with brownish-coloured liquid and without adhering to adjacent structures. The nephroblastoma diagnosis was obtained by histopathological exam. No adjuvant chemotherapy treatment was carried out. The patient presented a survival of 33 months.</p> 2020-06-16T00:00:00-03:00 Copyright (c) 2020 Dayane Caicó Collares Araujo, Michel Alves da Silva , Cristiano Chaves Pessoa da Veiga, Julio israel Fernandes http://rbmv.org/index.php/BJVM/article/view/1089 Sucessful of nitempyram in treatment occular myiasis in orbital cavity in dog – case report 2020-04-16T23:33:43-03:00 Fernando Rocha Miranda fernando_miranda02@hotmail.com Renan Bernardes Tavares renan_tavares94@hotmail.com Ciro Eugênio da Silva de Oliveira ciro.eugenio@gmail.com Emily Andressa Santos Lima emily.andressa@gmail.com Diefrey Ribeiro Campos diefrey8@hotmail.com Fabio Barbour Scott scott.fabio@gmail.com Julio Israel Fernandes vetjulio@yahoo.com.br <p>The aim of this study was to report the efficacy of nitempiram against Cochiliomiyia hominivorax larvae in ocular myiasis in a naturally infested dog. A female Beagle dog with occular miyasis was attended. After care and clinical examination, was found involvement of the entire ocular and periocular region. The animal was treated with nitenpyram, with a dose of 4,7 mg/kg, orally, jointly with analgesic medication. The expulsion and fall of live and dead larvae were evaluated, which were quantified every 15 minutes in the first hour and thereafter at 2, 3, 4, 6, 18 hours after treatment and subsequent manual removal of the larvae. Overall effectiveness was calculated, the larval expulsion rate and the larvicidal effect of nitenpyram. In full there were 140 larvae in the lesion, from which 90 live larvae were expelled, 46 dead larvae and 4 dead larvae mechanically removed, presenting 100% overall effectiveness, with larval expulsion activity of 97.1% and larvicidal efficacy of 35.7%. Based on the results obtained in this case, it can be concluded that nitenpyram has a fast-acting and safe action under <em>C. hominivorax </em>larvae, proving be a pleasant alternative therapeutic alternative for the elimination of myiasis in orbital cavity of dogs.</p> 2020-02-13T00:00:00-02:00 Copyright (c) 2020 Fernando Rocha Miranda, Renan Bernardes Tavares, Ciro Eugênio da Silva de Oliveira, Emily Andressa Santos Lima , Diefrey Ribeiro Campos, Fabio Barbour Scott, Julio Israel Fernandes http://rbmv.org/index.php/BJVM/article/view/1082 Thoracomelia in sheep: a case report 2020-07-01T11:56:23-03:00 Eder Sardinha Silva edersardinha@mpu.mp.br Vanessa Silva Mustafa nessamustafa@gmail.com Paula Aguiar Sá paulasavet@hotmail.com Rita de Cassia Campebell campbellvetdr@gmail.com <p>In this case report, the occurrence of thoracomelia in a female sheep is reported. Thoracomelia is a<br>congenital malformation that can affect several animal species and is characterized by the presence of<br>a supernumerary limb in the thoracic region. Scientific studies regarding the etiology of changes of this<br>nature are limited in veterinary medicine, especially concerning sheep. So far, there is no consensus<br>regarding if the origin of this congenital malformation is genetic or environmental. Here, we provide the<br>historical and photographic record of thoracomelia in a female sheep, and relate the malformation to an<br>environmental cause: physical aggression suffered during embryonic development. The sheep underwent<br>a surgical procedure for removal of the accessory limb and subsequently remained in the breeding line,<br>giving birth to healthy descendants without thoracomelia.</p> 2020-06-16T00:00:00-03:00 Copyright (c) 2020 Eder Sardinha Silva, Vanessa Silva Mustafa, Paula Aguiar Sá, Rita de Cassia Campebell http://rbmv.org/index.php/BJVM/article/view/1120 Mesenchymal Stromal/Stem cells: Historical perspective and ongoing challenges 2020-06-15T23:51:33-03:00 Maria Isabel Doria Rossi idrossi@hucff.ufrj.br Danielle Cabral Bonfim idrossi@hucff.ufrj.br <p>The potential of stem cell-based therapy was accompanied by high expectations and led, consequently, to an increase in clinical translational investments. Mesenchymal stem/stromal cells (MSCs) became the cell-based product most experimentally studied worldwide. However, uncertainties about the mechanisms and the in vivo identity of MSCs impose concerns about their large-scale use in regenerative medicine. This review comprises a historical summary on MSC, a critical discussion about their identity and function, and the ongoing challenges for their use in therapy and tissue bioengineering.</p> 2020-06-11T00:00:00-03:00 Copyright (c) 2020 Maria Isabel Doria Rossi, Danielle Cabral Bonfim