Retrospective study of canine mast cell tumor using two histopathological classification

  • Anna Paula Martins de Carvalho
  • Gabriella Massine Nogueira
  • Hassan Jerdy Leandro
  • Raphael Mansur Medina
  • Eulógio Carlos Queiróz de Carvalho
  • Andrigo Barbosa de Nardi
  • Leonardo Serafim da Silveira
Keywords: dog, histopathology, mast cell tumor, Patnaik, Kiupel.


The number of reported cancer in dogs is increasing every year and the mast cell tumor is the most
common skin tumor. There are few reports regarding tumor characteristics in Brazil. This study aimed to
conduct a retrospective study of animals with mast cell tumors treated at the Veterinary Hospital of UENF.
Evaluation of gender, breed, age, tumor location and histological grade by Kiupel and Patnaik was ratings
of 61 animals. Males were the majority (59%) of animals and elderly patients aged between 7 and 12 years
were the most affected. Most dogs were mixed breed, Boxer, Labrador and Pinscher. The region members
(38.5%), followed by tumors in the trunk (27%) and genital tumors (13.1%) were the most common tumor
localization. Animals with multiple tumors were also reported (13.4%). Six tumors were classified as grade
I, 45 grade II and 10 as grade III. According to Kiupel classification, most tumors (68.85%) were classified
as low grade. By this study it can be seen that the older animals were the most affected, race and location
are related to the histological grade and the most common were the grade II and the low grade

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