Expression of syndrome paraneoplastic in a dog with cutaneous hemangiosarcoma: case report

  • Alricélia da Silva Camboim
  • Márcio Eduardo Melo Benvenutti
  • Ermano Lucena de Oliveira
  • Antônio Fernando de Melo Vaz
  • Rosangela Maria Nunes da Silva
  • Antônio Flavio Medeiros Dantas
  • Almir Pereira de Souza
Keywords: neoplasia, blood count, skin, biopsy, cytology, canine.


Our objective in this work was to report a case of cutaneous hemangiosarcoma in a dog, emphasizing the clinical and pathological aspects and paraneoplastic changes associated with this neoplasia. On physical examination, there was an irregular nodule of 2.5 cm × 2.0 cm, elastic firm, dark red, stuck, ulcerated, right on the side of the prepuce. Blood count was conducted, serum levels of urea, creatinine, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), glucose, total protein (TP), albumin, globulin, C reactive protein, Ca+, Na+, K+, Cl- and P. We also did the evaluation of clinical parameters heart rate, respiratory rate, body temperature and measurement of arterial blood pressure. Other tests performed included cytology of the tumour mass, chest x-ray, abdominal ultrasound, and electrocardiogram. Blood count changes observed were eosinophilia and lymphopenia, serum tests were within the reference standards for the species, there were no metastases on imaging studies as well there were no electrocardiographic changes. The animal underwent surgery for resection of the tumour and performed a histological examination, which confirmed the diagnosis of cutaneous hemangiosarcoma. We could conclude that one should include eosinophilia and lymphopenia as paraneoplastic manifestations in animals with cutaneous hemangiosarcoma. 

How to Cite
Camboim, A. da S., Benvenutti, M. E. M., de Oliveira, E. L., Vaz, A. F. de M., da Silva, R. M. N., Dantas, A. F. M., & de Souza, A. P. (2018). Expression of syndrome paraneoplastic in a dog with cutaneous hemangiosarcoma: case report. Brazilian Journal of Veterinary Medicine, 39(2), 126-132.
Case report

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