Evaluation of antibodies elicited by a new recombinant antigen for Feline Leukemia Virus (FeLV) infection diagnostic

  • Nadia Rossi de Almeida
  • Maria das Graças Miranda Danelli
  • Mitika Kuribayashi Hagiwara
  • Ana Carolina Magalhães Andrade de Góes
  • Marco Alberto Medeiros
  • Carlos Mazur
Keywords: FeLV, cats, IFA, leukemia

Abstract

ABSTRACT. Almeida N.R., Danelli M.G.M., Hagiwara M.K., Góes A.C.M.A., Medeiros M.A. & Mazur C. Evaluation of antibodies elicited by a new recombinant antigen for Feline Leukemia Virus (FeLV) infection diagnostic. [Avaliação de anticorpos extraídos de um novo antígeno recombinante para o diagnóstico da infecção pelo Vírus da Leucemia Felina (FeLV).] Revista Brasileira de Medicina Veterinária, 35(Supl.2):95-99, 2013. Programa de Pós-graduação em Ciências Veterinárias, Instituto de Veterinária, Anexo 1, Universidade Federal Rural do Rio de Janeiro, BR 465 Km 7, Campus Universitário, Seropédica, RJ 23897-970, Brasil. E-mail: nadia.ufrrj@gmail.com A novel recombinant Feline Leukemia Virus (FeLV) capsid antigen was developed and inoculated in rabbits to elicit antibodies against it. These antibodies were evaluated by indirect immunoflourescence assay (IFA) and proved to react with the native FeLV antigen in agreement with the previous tests performed in animal samples. Considering its advantages to Brazilian scenario, the established IFA using recombinant antigen may be a practical and low cost diagnostic test to be incorpored as diagnosis of Feline Leukemia Virus.

Published
2014-03-12
How to Cite
de Almeida, N. R., Danelli, M. das G. M., Hagiwara, M. K., de Góes, A. C. M. A., Medeiros, M. A., & Mazur, C. (2014). Evaluation of antibodies elicited by a new recombinant antigen for Feline Leukemia Virus (FeLV) infection diagnostic. Brazilian Journal of Veterinary Medicine, 35(Supl.2), 95-99. Retrieved from http://rbmv.org/index.php/BJVM/article/view/663

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