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ABSTRACT. Atallah F.A., Estupiñan O.F.T., Ramos R.M.., Vale F.D., Silva S.J.Q., Costa D.R.G., Antunes F. & Oliveira A.L.A. [Use of acrylic resin in the reconstruction of the hard palate after nasal carcinoma resection in a dog - a Case report]. Uso de resina acrílica na reconstrução do palato duro após exérese de carcinoma nasal em cão - Relato de caso. Revista Brasileira de Medicina Veterinária, 35(Supl. 1):112-117, 2013. Curso de Pós-Graduação em Ciência Animal, CCTA, Sala 207-A, Universidade Estadual Norte Fluminense Darcy Ribeiro, Av. Alberto Lamego, 2000, Parque Califórnia, Campos dos Goytacazes, RJ 28013-602, Brasil. E-mail: firstname.lastname@example.org Neoplasia of the nasal cavity are uncommon in domestic animals, although they represent only 1% of all tumors affecting the dog, tumors of the nasal cavity and paranasal sinuses comprise about 59% to 82% of all tumors of the respiratory tract canine. Consequently the position adjacent to the brain and eyes, nasal neoplasms are in a critical place, however, treatment is focused on controlling the site of injury. The preferred treatment involves radical resection of the neoplasm by rhinotomy. After surgical excision of the tumor on the hard palate, anatomical changes originate, being necessary the use of a palatal prosthesis. The objective of this study is to report the use of acrylic resin as an effective alternative for the reconstruction of bone defects created by wide resection of squamous cell carcinoma of the hard palate in a dog race doberman. At physical examination, the animal showed respiratory system changes with clinical signs of a cough, rhinorrhea, and rales on auscultation. The histopathological examination and rhinoscopy revealed the presence of squamous cell carcinoma of approximately 4 cm. respectively. Two approaches were used, the ventral rhinostomy like a palliative procedure, and chemotherapy like prophylactic treatment. The denture acrylic resin was used to reduce the palate, being effective during the time of survival.