Aspergillus fumigatus in ovine lung in Brazil - Case report

  • Huber Rizzo

Abstract

ABSTRACT. Rizzo H., Silva Júnior V., Mota R.A., Rocha L.L.L., Ono M.S.B., Cruz J.A.L. de O., de Torres S.M., Coutinho L.C. de A., Guimarães J.A. & Dantas A.C. [Aspergillus fumigatus in ovine lung in Brazil - Case report.] Aspergillus fumigatus em pulmão de ovino no Brasil - Relato de caso. Revista Brasileira de Medicina Veterinária, 38(4):413-419, 2016. Departamento de Medicina Veterinária, Universidade Federal Rural de Pernambuco, Rua Dom Manoel de Medeiros s/n, Recife, PE 52171-900, Brasil. E-mail: hubervet@gmail.com

Its described a case of mycotic pneumonia caused by Aspergillus fumigatus in a three months old sheep, that died during the treatment period at the AGA/DMV/UFRPE consequence of skin lesions caused by dog attack. The animal did not respond to antibiotic treatment base on florafenicol, keeping high leukometric values. Macroscopically the lungs showed multifocal areas of cheesy aspect, varing shape and sizes, with yellowish tinge to the center and red at the edges. Microscopically were found granulomatous lesion with extensive dystrophic calcification area, presence of fibrin exudate in the bronchi, inflammatory infiltration of mononuclear diffuse, fibroblast proliferation delimiting a capsule around the inflammatory foci, epiteliodida robe with negative images of hyphae in the lung parenchyma, foamy macrophages, but no giant cells were seen. The blood culture on agar revealed the development of filamentous fungus with grayish color and lots of aerial hyphae, and the culture on Sabouraud media were seen colonies of dark green color with whitish borders both compatible with macromorphology colonies of A. fumigatus . The micromorphology of fungal growth revealed vesicles stick format with sporulation begins in the upper half of the vesicles. The imprints of nodular lesions of the lungs on slides, through panotic dye, showed septate hyphae and branched invading the tissue. Pulmonary infection by A. fumigatus, showed fatal and resistant to treatment with florafenicol, and the diagnosis was based on the cultivation of nodular lesions in appropriate media and histopathology.

Published
2016-12-16

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