Multicentric lymphoma in a Brazilian Warmblood Horse - Case report

  • Luana Alves Freitas da Silva
Keywords: Lymphoma, neoplasia, horse


ABSTRACT. da Silva L.A.F., Guttmann M., de Carvalho e Suzano S.M., Lessa D.A.B. & Alencar N.X. Multicentric lymphoma in a Brazilian Warmblood Horse - Case report. [Linfoma multicêntrico em um cavalo da raça Brasileiro de Hipismo - Relato de caso.] Revista Brasileira de Medicina Veterinária, 38(4):393-396, 2016. Faculdade de Veterinária, Universidade Federal Fluminense, Rua Vital Brasil Filho, 64, Santa Rosa, Niterói, RJ 24230-340, Brasil. E-mail:

Lymphoma is a malignant neoplasia and the multicentric form is the most common presentation in horses. This paper describes the clinical and pathological findings of a multicentric lymphoma in a horse, emphasizing the laboratorial findings. A 13-year-old Brazilian Warmblood horse presented with a previous ultrasonography diagnosis of spleen neoplasia. The horse had muscle mass loss, polyuria and polydipsia, pitting lower limb edema, irregular thermoregulation, abdominal discomfort and selective appetite. Laboratory exams revealed occasional anemia, absolute lymphopenia, hyperproteinemia with hyperglobulinemia and alpha portion increase, as well as increase in AST, GGT, triglycerides, cholesterol and bilirubin. Glycaemia was constantly low. The horse was humanely euthanized after clinical deterioration at the end of a 60-day period. At necropsy, the spleen was increased in size, and had multiple nodules. Microscopic analysis of the nodules characterized large cell lymphoma. Since neoplasias are not frequent in this species, case reports help reaching a diagnosis. Laboratory exams during the disease are useful to monitor progression and in clinical decision-making.