Results of laboratory diagnosis of rabies in herbivores (cattle and horses): a retrospective study

  • Noelle de Castro Barrosa Eloisa Maria de Castro
  • Helio Langoni Unesp
  • Cassiano Victória
  • Benedito Donizete Menozzi UNESP
  • Karine Bott Mantovan
  • Giulia soares Latosinski Unesp/Botucatu,SP.
  • Samea Fernandes Joaquim Unesp/Botucatu,SP
Keywords: rabie, zoonosis, bovine, equine


Rabies is a zoonosis of extreme importance to public health. Specifically in herbivores, it causes economic losses, considering its lethality. The diagnosis provides information to describe the epidemiology of the disease in the regional study. For this purpose, a survey of Central Nervous System (CNS) materials, received for diagnosis in the Center-West region of the State of São Paulo, by the Zoonosis Diagnostic Service (SDZ), Faculdade de Medicina Veterinária e Zootecnia (FMVZ) - UNESP-Botucatu-SP. In the period from 2001 to 2015, a total of 643 samples were analyzed, being 489 (76.05%) of the bovine species, with 68 (13.9%) positive samples and 154 (23.95%) of the equine species with 17 (11.3%) positive. For the analyzed bovine samples, sensitivity and specificity values of the fluorescent antibody test (FAT) were 88.24 and 99.52% respectively and for equines, 47.06 and 100.0%. The frequency of samples received by species, month, and year and the results of the diagnostic tests recommended by the World Health Organization (WHO), fluorescent antibody test (FAT) and the mouse inoculation test (MIT), were analyzed.

Author Biographies

Noelle de Castro Barrosa, Eloisa Maria de Castro

Residente em Zoonose e Saúde Pública-DHVSP-FMVZ-Unesp/Botucatu

Helio Langoni, Unesp

Professor titular da Disciplina de Zoonoses-DHVSP-FMVZ-Unesp / Botucatu, SP.

Benedito Donizete Menozzi, UNESP

Assistente de Suporte Acadêmico III - DHVSP-FMVZ - Unesp / Botucatu

Giulia soares Latosinski, Unesp/Botucatu,SP.

Residente em Zoonose e Saúde Pública-DHVSP-FMVZ-Unesp/Botucatu

Samea Fernandes Joaquim, Unesp/Botucatu,SP

Residente em Zoonose e Saúde Pública-DHVSP-FMVZ-Unesp/Botucatu

Scientific articles