ACQUIRED MYASTHENIA GRAVIS IN DOG – CASE REPORT

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Maria Eduarda dos Santos Lopes Fernandes
https://orcid.org/0000-0003-1414-2475
Brock G.W.
https://orcid.org/0000-0001-6764-8256
Peixoto A.J.
https://orcid.org/0000-0002-4861-7726
Corrêa C.G.
https://orcid.org/0000-0003-3307-7736
Oliveira P.
https://orcid.org/0000-0002-4004-7853
Adeodato A.G.
https://orcid.org/0000-0002-6918-6515
Silva M.F.A.
https://orcid.org/0000-0002-5651-3855
Coelho C.M.M.
https://orcid.org/0000-0003-1205-8413

Abstract

Neuromuscular diseases are uncommon in the clinical routine of dogs and cats and their diagnosis is a challenge for the veterinarian. Thus, this paper reports the clinical diagnosis and established therapy in a four-year-old female without a defined breed with a history of ataxia and tetraparesis, especially after exercise. Due to the history and clinical signs presented, acquired myasthenia gravis was suspected and the therapeutic diagnosis was chosen using anticholinesterase neostigmine, for being simpler, faster and more accessible. The patient presented a significant improvement in clinical status after administration of neostigmine intramuscularly, returning to normal ambulatory activity after administration of the drug intravenously, thus making possible the diagnosis of the disease. Treatment was instituted using pyridostigmine bromide associated with corticosteroid in a immunosuppressive dose for a period of six months, observing complete remission of the clinical signs without recurrences until the present moment.

Article Details

How to Cite
dos Santos Lopes Fernandes, M. E., Wacheleski Brock, G., Rodrigues Peixoto, A. J., Gonring Corrêa, C., de Oliveira, P., Gradowski Adeodato, A., Albuquerque da Silva, M. F., & Molinaro Coelho, C. M. (2020). ACQUIRED MYASTHENIA GRAVIS IN DOG – CASE REPORT. Brazilian Journal of Veterinary Medicine, 42(1), e106320. https://doi.org/10.29374/2527-2179.bjvm106320
Section
Case report

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